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KMID : 1101420190510020145
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Korean Journal of Clinical Laboratory Science
2019 Volume.51 No. 2 p.145 ~ p.154
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Relationship between the Estimated Glomerular Filtration Rate and the Urine Microalbumin/Creatinine Ratio and Ferritin in Korean Adults
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Yoon Hyun
Lee Jun-Ho
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Abstract
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This study examined the relationship between the estimated glomerular filtration rate (eGFR) and urine microalbumin/creatinine ratio (uACR) with ferritin in Korean adults. This study included 4,948 adults aged ≥20 years from the 2012 Korea National Health and Nutrition Examination Survey (KNHANES) data. A covariance test adjusted for covariates was performed for the ferritin levels in relation to the decreased eGFR (eGFR<60 ml/min/1.73 m2) and elevated uACR (uACR≥30 mg/g). Several key findings were made in the present study. First, after adjusting for the related variables, the ferritin level was higher in the decreased eGFR group [103.04±6.59 mL/min/1.73 m2; 95% confidence interval (CI), 90.12∼115.96] than in the normal eGFR group (84.87±1.16 mL/min/1.73 m2; 95% CI, 82.59∼87.14; P=0.007). Second, after adjusting for the related variables, the ferritin level (M±SE) was similar in the normal uACR group (85.70±1.20 mg/g; 95% CI, 83.35∼88.05) and elevated uACR group (82.72±4.09 mg/g; 95% CI, 74.71∼90.73) (P=0.487). Chronic kidney disease was positively associated with the ferritin level in Korean adults but albuminuria was not.
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KEYWORD
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Ferritin, Glomerular filtration rate, Urine microalbumin/creatinine ratio
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